Blog
The Department of Catalysis and Chemical Reaction Engineering at the National Institute of Chemistry is a project partner cooperating on Biopharm.si projects RRP4, RRP6, RRP7. Our main tasks are related to the simulation of biological drug production process. Results of our study will serve as a tool for biopharmaceutical process development integrating up-stream and down-stream processes, and for further optimization, monitoring, and quality control.
Figure 1: Department of Catalysis and Chemical Reaction Engineering at the Slovenian Chemical Society Annual Meeting 2017 in Portoroz. Biopharm.si team are represented by Miha, Miša, Drejc and Uroš.
- dynamical concentration profiles of components in the cell and the cell medium,
- simulations of the cell medium modification, such as cell feeding, which enables smart experiment design,
- a link to the down-stream processes and to novel (bio)process design via protein N-glycosylation coupling.
Figure 2: Coupling of Cell metabolism and protein N-glycosylation. The end products are glycans (biological drugs).
From left to rigth: chemist Miha (the authentic mastermind), biologist Miša (she knows what animals need, so she eats their food), astrophysicist Drejc (doing some stretching before running Monte Carlo) and chemical engineer Uroš (playing with animals in the park)
Iskanje
Zadnje
- Workshop on "High Content Imaging and Data Science for Virtual Screening and Drug Discovery"
- VIS-NIR Low-cost Raman spectrometer
- Continuous bioprocess of bacteria and bacteriophages
- CRISPR/Cas9 tool for Genome Editing
- What researchers do at the Department of Catalysis and Chemical Reaction Engineering