RDP1: Cell Line Quality Control for Biologics Production

Selection of best-performing cell lines for manufacturing is one of the first, but most resource demanding steps in the biologics process development. The goal of the project is to identify critical quality control  parameters on the gene and metabolite activities levels that will allow for fast and efficient development of production Chinese hamster ovary (CHO) cell lines. Additionally, we will develop methodologies to optimize the setup of production bioprocess itself.

Project leader: dr. Kristina Gruden

Project partners: Lek , National Institute of Biology , BIA